This document outlines candidacy, preparation, scheduling, recovery, and the normal stages of healing for patients undergoing a 2-day Croton oil/phenol peel.

I. Indications for This Peel

This peel is typically recommended for patients with:

  • Advanced skin aging, including deep wrinkles and significant facial skin laxity
  • Severe acne scarring

II. Consultation (Telemedicine or In-Person)

A. Qualification Criteria

To be considered a good candidate, you should:

  1. Be medically healthy
  2. Have a strong psychological profile and realistic expectations
  3. Have the appropriate indication for a deep chemical peel
  4. Be able to commit to the required recovery downtime

III. Pre-Operative Requirements

Before the procedure, the following are required:

  • EKG and blood tests to evaluate liver and kidney function
  • High-quality baseline photographs for your medical chart
  • A reliable support person for the first 3–4 days, including a driver
  • Preparation for a liquid diet lasting approximately 7–10 days
  • Prescriptions filled for:
    • Antiviral medication
    • Antibiotics
    • Antifungal medication
    • Anti-nausea medication
    • Pain medication
    • Sleep aids
  • Review and understanding of all pre- and post-operative instructions (both patient and assistant/support person)

IV. Arrangements to Make in Advance

Please plan for the following:

  • Receive the post-operative care kit provided by our office
  • Arrange to take two weeks off work
  • Light online work may be resumed around Day 4 if tolerated
  • Reserve a hotel near Dr. Rullan’s office for approximately 3 days
  • Have direct access to Dr. Rullan’s cell phone and be prepared to text daily photos
  • Driving home is usually permitted on Day 4
  • Flying home is usually permitted on Days 8–9, once the mask has naturally detached

V. Procedure and Recovery Timeline

A. Procedure Schedule

  • Day Before the Peel: Begin antiviral medication
  • Day 1:
    • Approximately 2 hours in the operating room
    • IV sedation administered by an RN
    • You will leave with tape applied to the face (Figure1)
  • Day 2:
    • Approximately 1 hour in the operating room
    • IV sedation administered by an RN
    • You will leave with a powder mask, forming the protective mask (Fig. 2)

B. Early Recovery

  • Day 3:
    • Typically the most uncomfortable day
    • Expect significant pain, swelling, and skin drainage (Fig. 3)
  • Day 4:
    • Symptoms usually begin to improve
    • Less drainage and discomfort (Fig. 4)
    • Begin using diluted vinegar/antibiotic spray or compresses
    • If you notice a white exudate. In. the eylid region, begin cleaning that area with dilute. Hydrogen peroxide, gently rolling a Qtip over it.
    • Apply Aquaphor around the eyes( if it looks clean) and lips

C. Days 5–7: Infection Monitoring

  • This is the period of highest infection risk, especially around the eyes (Fig.5)
  • Be prepared to start ciprofloxacin (Cipro) pills and eye drops if instructed by Dr. Rullan
  • If the mask becomes overly dry and cracks: (Fig. 6)
    • Spray with the vinegar/water solution
    • Apply a small amount of Aquaphor directly to the crack if advised
    • Never apply Aquaphor over infected skin (whitish exudate).

Signs of Infection

  • White or yellowish, moist scabbing (Fig. 7)

Care Instructions

  • Gently dab the area with a Q-tip moistened with diluted hydrogen peroxide several times daily
  • Follow with an antibiotic powder and/or Silver balm
  • Never forcibly remove a scab, even if it appears dark or dry (Fig. 8)
  • Infection or scratching can result in permanent scarring (see Figs,13)

D. Days 7–10: Mask Separation

  • After reviewing your daily photos, Dr. Rullan may advise: (Fig. 9)
    • Taking a warm shower
    • Shampooing is allowed, but avoid direct water spray on the face
    • Allow water to gently run over the face
  • The goal is to soften the mask, allow it to dry again, and encourage natural separation
  • Never pull off areas of the mask that are firmly attached
  • As healing progresses, the mask will release and wash away on its own (Fig. 10)
  • Between Days 7–10, you will visit the office so Dr. Rullan or his assistant can safely remove any portions that are ready

E. Skin Care After Mask Removal

  • Once approximately 90% of the mask has detached, begin using the Skin Repair System included in your kit (Fig. 11)
  • Apply Aquaphor only to areas that remain extremely dry or sensitive

VI. Stages of Skin Healing

A. Immediate Post-Mask Phase

  • The mask is removed and you begin the prescribed skin healing regimen

B. Sensitivity, Dryness, and Itching (Fig.12)

  • Tightness, dryness, and itching are common
  • Helpful treatments include:
    • Diluted vinegar/water compresses
    • Antihistamines
    • Prednisone (if prescribed)
    • Topical cortisone cream

C. Redness (Erythema) (Fig 12)

  • Prolonged redness is the most common concern
  • It indicates active healing with increased growth factors, collagen formation, and new blood vessels
  • Redness may worsen with heat and exercise; lighter activity is recommended
  • Treatments that may help:
    • Topical cortisone creams
    • Tinted green sunscreen
    • Vascular lasers (e.g., V-Beam, DermaV), when performed regularly
    • Medical-grade makeup (e.g., Oxygenetix, Dermablend)
    • Exosome serum
    • CO₂ Lift gel (very soothing; ask our staff)

D. Skin wounds with infection. Will need management ASAP (Fig 13 x3)

E. Post-Inflammatory Hyperpigmentation (Brown Discoloration) (Fig 14)

  • Typically appears about 1 month after the peel, often along the cheekbones
  • May respond to:
    • Cortisone creams
    • Hydroquinone-based products
    • Exosome serum

F. Temporary Lightening of Skin Tone (Fig.15)

  • Lighter-than-normal skin tone is common for several months
  • Improvement may be supported by:
    • Tretinoin
    • Microneedling
    • Bimatoprost (prescription)

G. Long-Term Results (Fig. 16)

  • Patients with normal skin tones typically achieve the best overall results
  • Significant improvement is usually visible within 2–3 months
  • Final results—normal skin tone, improved acne scarring, and enhanced skin quality—continue to develop for up to 12 months after the peel